Mariusz L Hartman Selected Research

17-aminogeldanamycin

5/2020	17-Aminogeldanamycin Inhibits Constitutive Nuclear Factor-Kappa B (NF-κB) Activity in Patient-Derived Melanoma Cell Lines.
1/2019	17-Aminogeldanamycin selectively diminishes IRE1α-XBP1s pathway activity and cooperatively induces apoptosis with MEK1/2 and BRAFV600E inhibitors in melanoma cells of different genetic subtypes.

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Mariusz L Hartman Research Topics

Disease

21	Melanoma (Melanoma, Malignant) 01/2021 - 04/2013
12	Neoplasms (Cancer) 01/2021 - 10/2012
2	Skin Neoplasms (Skin Cancer) 05/2020 - 02/2015
2	Hypoxia (Hypoxemia) 08/2019 - 06/2015
1	Carcinogenesis 04/2020
1	Hyperoxia 08/2019
1	Neoplasm Metastasis (Metastasis) 05/2016
1	Adenocarcinoma 05/2016
1	Papillary Thyroid Cancer 05/2016
1	Oncogene Addiction 02/2015

Drug/Important Bio-Agent (IBA)

9	Pharmaceutical PreparationsIBA 01/2021 - 09/2013
9	trametinibIBA 07/2020 - 02/2016
7	VemurafenibIBA 07/2020 - 01/2017
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 10/2012
5	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 04/2020 - 02/2016
4	CateninsIBA 01/2017 - 01/2014
4	Microphthalmia-Associated Transcription FactorIBA 02/2016 - 01/2014
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 05/2020 - 09/2013
3	Interleukin-8 (Interleukin 8)IBA 05/2020 - 09/2013
3	Complement System Proteins (Complement)IBA 01/2019 - 10/2012
3	parthenolideIBA 02/2016 - 08/2013
2	Messenger RNA (mRNA)IBA 07/2020 - 01/2015
2	Heat-Shock Proteins (Heat-Shock Protein)IBA 05/2020 - 01/2019
2	17-aminogeldanamycinIBA 05/2020 - 01/2019
2	Oncogene Proteins (Oncogene Protein)IBA 01/2020 - 01/2019
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2020 - 01/2017
2	Epidermal Growth Factor (EGF)IBA 01/2017 - 01/2015
2	Transcription Factors (Transcription Factor)IBA 06/2015 - 04/2015
1	encorafenibIBA 01/2021
1	NF-kappa B (NF-kB)IBA 05/2020
1	Oxygen (Dioxygen)IBA 08/2019
1	NAD (NADH)IBA 01/2019
1	geldanamycinIBA 01/2019
1	quinone (benzoquinone)IBA 01/2019
1	Oxidoreductases (Dehydrogenase)IBA 01/2019
1	Biomarkers (Surrogate Marker)IBA 01/2019
1	Caspase 3 (Caspase-3)IBA 01/2019
1	Adapalene (Differin)FDA LinkGeneric 01/2017
1	Proto-Oncogene Proteins B-rafIBA 05/2016
1	ElementsIBA 05/2016
1	Protein Isoforms (Isoforms)IBA 02/2016
1	Biological ProductsIBA 06/2015
1	Dacarbazine (DIC)FDA LinkGeneric 09/2013
1	Alkylating AgentsIBA 09/2013
1	Doxorubicin (Adriamycin)FDA LinkGeneric 08/2013
1	SurvivinIBA 04/2013
1	Apoptosis Regulatory ProteinsIBA 04/2013

Therapy/Procedure

14	Therapeutics 01/2021 - 10/2012
2	Immunotherapy 04/2020 - 01/2019
1	Radiotherapy 02/2015
1	Drug Therapy (Chemotherapy) 08/2013